Jordan's Syndrome Research Team

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An International Dream Team

PPP2R5D Researchers

Top researchers from around the globe are assembling to examine the link between a known PPP2R5D gene variation identified in children and neurodevelopmental disorders including autism, intellectual disabilities, behavioral challenges and seizures.

The international team of human geneticists, neurologists, psychologists, biochemists, protein modelers, model organism researchers and cancer biologists aim to study the mechanism of the gene variation to gain a deeper understanding and develop possible treatments for the future.

Scientific Team

wendy

Dr. Wendy Chung, MD, PhD

Columbia University

Overall Study Principal Investigator
Mirzaa

Dr. Ghayda Mirzaa, MD

Seattle Children's Hospital

Clinical and Molecular Spectrum of PP2A Related Disorders
Cho

Megan Cho

GeneDx

Genetic Counselor
Janssens

Dr. Veerle Janssens, PhD

KU, Leuven

Signaling functions of PP2A in cancer cells, in neuronal processes and neurologic diseases
Honkanen

Dr. Richard Honkanen, PhD

University of South Alabama

Ser/Thr phosphatase inhibitors and high throughput screens
Strack,Stefan

Dr. Stefan Strack, PhD

University of Iowa

Protein phosphatase 2A in neuronal signal transduction
Xing

Dr. Yongna Xing, PhD

University of Wisconsin-Madison

PP2A structural biologist
Wadzinski

Dr. Brian Wadzinski, PhD

Vanderbilt University

PP2A cell biology in Drosophila
xia

Dr. Houhui (Hugh) Xia, PhD

University of Rochester

PP1 in the nervous system; mouse models with altered PPase activity in the brain; electrophysiology and behavior
Kyle Fink

Dr. Kyle Fink, PhD

UC Davis Neurology and
Institute of Regenerative Cures

Stem Cell Program
Jan Nolta

Dr. Jan Nolta, PhD

UC Davis Institute
for Regenerative Cures

Stem Cell Program
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